Factores asociados al síndrome de Wellens en pacientes con síndrome coronario agudo sin elevación del segmento ST / Factors associated to Wellens' syndrome in patients with acute coronary syndrome without ST-segment elevation

Introducción: El síndrome de Wellens constituye un equivalente del síndrome coronario agudo con elevación del segmento ST. Este incluye dos patrones electrocardiográficos que sugieren lesión crítica de la arteria descendente anterior. Objetivo: Evaluar probables factores asociados al síndrome de Wellens en pacientes con síndrome coronario agudo sin elevación del segmento ST y lesiones coronarias significativas en la arteria descendente anterior. Material y métodos: Se realizó un estudio observacional, analítico, transversal en pacientes con diagnóstico de síndrome coronario agudo sin elevación del ST y lesión significativa en la arteria descendente anterior, comprobada mediante coronariografía, ingresados en la unidad de cuidados coronarios intensivos del Hospital Clínico-Quirúrgico Manuel Fajardo entre el 2016 y 2019. Resultados: La edad media fue de 66 años, predominó el sexo masculino (53,9 por ciento) y el antecedente de hipertensión arterial (89,5 por ciento). Los pacientes con síndrome de Wellens tuvieron un significativo menor porcentaje de antecedente de cardiopatía isquémica (58,1 por ciento vs. 84,8 por ciento; p = 0,012). Además, el síndrome arrojó asociación estadísticamente muy significativa con la condición de fumador activo (51,2 por ciento vs. 15,2 por ciento; p < 0,01). No se encontró relación estadística significativa entre el síndrome de Wellens y el resultado angiográfico. Conclusiones: La presencia de los patrones electrocardiográficos del síndrome de Wellens se asocia con el hábito tabáquico en pacientes con síndrome coronario agudo sin elevación del segmento ST y lesiones coronarias en la arteria descendente anterior, y su ausencia se asocia con el antecedente de cardiopatía isquémica en el mismo subgrupo de individuos(AU)

Introduction: Wellens' syndrome is equivalent to acute coronary syndrome with ST-segment elevation. It includes two electrocardiographic patterns suggesting a critical lesion in the anterior descending artery. Objective: Evaluate probable factors associated to Wellens' syndrome in patients with acute coronary syndrome without ST-segment elevation and significant coronary lesions in the anterior descending artery. Methods: A cross-sectional observational analytical study was conducted of patients diagnosed with acute coronary syndrome without ST-segment elevation and significant lesion in the anterior descending artery verified by coronary arteriography, admitted to the intensive coronary care unit at Manuel Fajardo Clinical Surgical Hospital in the period 2016-2019. Results: Mean age was 66 years, with a predominance of the male sex (53.9 percent) and a history of hypertension (89.5 percent). Patients with Wellens' syndrome had a significantly lower percentage of ischemic heart disease antecedents (58.1 percent vs. 84.8 percent; p = 0.012). A very significant statistical association was observed between the syndrome and active smoking (51.2 percent vs. 15.2 percent; p < 0.01). A significant statistical relationship was not found between Wellens' syndrome and angiographic results. Conclusions: The presence of electrocardiographic patterns of Wellens' syndrome is associated to smoking in patients with acute coronary syndrome without ST-segment elevation and coronary lesions in the anterior descending artery, whereas their absence is associated to a history of ischemic heart disease in the same subgroup of individuals(AU)

Terapia endovascular en trauma periférico: una alternativa a la cirugía abierta tradicional / Endovascular therapy in peripheral trauma: our experience

Resumen Introducción: La terapia endovascular ha demostrado ser una buena alternativa de tratamiento en las enfermedades arteriales y venosas. Asimismo, en trauma vascular periférico constituye una excelente opción, especialmente en sitios anatómicos difíciles de acceder y con lesiones complejas como seudoaneurismas, fístulas arteriovenosas (FAV) o la combinación de ambos, con numerosas ventajas. Objetivo: Evaluar los resultados del tratamiento endovascular en trauma vascular penetrante por agresiones y iatrogenias. Materiales y Método: Revisión retrospectiva de todos los pacientes con trauma vascular periférico sometidos a terapia endovascular. Resultados: Entre abril de 2011 y mayo de 2020 se trataron 30 pacientes, 28 hombres y 2 mujeres. Con edades fluctuantes entre 17 y 84 años. La causa del trauma fue 20 penetrantes y 10 iatrogenias. Los vasos afectados fueron arteria femoral superficial 6, femoral profunda 2, subclavia 9, axilar 1, poplítea 4, ilíacas 1, peronea 1, tibial anterior 5, tronco venoso braquiocefálico 1. Diecisiete pacientes fueron tratados con endoprótesis, 9 con embolización y 4 con cierre percutáneo en relación con catéteres arteriales en subclavia. No hubo mortalidad, pero dos pacientes requirieron reparación abierta: un seudoaneurisma poplíteo gigante y un seudoaneurisma de tibial anterior, en ambos se constató sección completa de ambas arterias. El seguimiento clínico ha sido entre 30 días y 3 años. Conclusiones: En esta serie de casos, la terapia endovascular en lesiones de trauma vascular periférico ofrece excelentes resultados con baja morbimortalidad y permeabilidad aceptable a corto y mediano plazo.

Introduction: Endovascular therapy has proven to be a good treatment alternative in arterial and venous diseases. Likewise, in peripheral vascular trauma it is an excellent option, especially in anatomical sites that are difficult to access and with complex lesions such as pseudoaneurysms, arteriovenous fistulas (AVFs) or the combination of both, with numerous advantages. Aim: To evaluate the results of endovascular treatment in trauma Penetrating vascular injury and iatrogenesis. Materials and Method: Retrospective review of all patients with peripheral vascular trauma undergoing endovascular therapy. Results: Between April 2011 and May 2020, 30 patients were treated, 28 men and 2 women. With fluctuating ages between 17 and 84 years. The cause of the trauma was 20 penetrating and 10 iatrogenic. The affected vessels were superficial femoral artery 6, deep femoral 2, subclavian 9, axillary 1, popliteal 4, iliac 1, peroneal 1, anterior tibial 5, brachiocephalic venous trunk 1. Seventeen patients were treated with endoprosthesis, 9 with embolization and 4 with percutaneous closure in relation to arterial catheters in the subclavian. There was no mortality but two patients required open repair: a giant popliteal pseudoaneurysm and an anterior tibial pseudoaneurysm in which both sections of both arteries were found to be complete. Clinical follow-up was between 30 days and 3 years. Conclusión: In this serie, endovascular therapy in peripheral vascular trauma lesions offers excellent results with low morbidity and mortality and acceptable patency in the short and medium term.

Embolization in patient with hypovolemic shock after transobturator sling procedure / Embolização após sling transobturatório em paciente com choque hipovolêmico

Abstract The placement of a suburethral sling is standard treatment for stress urinary incontinence. The transobturator technique (TOT) emerged as an alternative to minimize the risks of the blind insertion of needles, leading to a lower rate of perforation complications compared with the retropubic approach. We present a case of injury to a branch of the left obturator artery following the placement of a urethral sling using TOT, followed by intense bleeding and hemodynamic instability, which was treated with embolization.

Resumo Sling de uretra média é o tratamento padrão para a incontinência urinária de esforço. A abordagem transobturatória (TOT) surgiu como alternativa para minimizar os riscos da inserção às cegas das agulhas com taxa de complicações perfurativas menores quando comparadas à abordagem retropúbica. Apresentamos um caso de lesão em ramo da artéria obturatória esquerda após sling TOT que evoluiu com sangramento intenso e instabilidade hemodinâmica, sendo tratado com embolização.

Trauma vascular na Amazônia: atualizando o desafio / Vascular trauma in the Amazon: updating the challenge

RESUMO Objetivo: avaliar dados epidemiológicos dos pacientes operados por trauma vascular em hospital de referência para traumatismos vasculares do Estado do Pará, determinar as variáveis que aumentam o risco de óbito e fazer uma análise comparativa com os resultados previamente publicados pela mesma instituição. Métodos: estudo retrospectivo analítico realizado através da coleta de dados de pacientes operados por lesões vasculares, entre março de 2013 e março de 2017. Foram analisados dados demográficos e epidemiológicos, como o mecanismo e topografia da lesão, distância entre o local do trauma e o hospital, tipo de tratamento e complicações. Foi feito ainda o estudo de uma matriz de correlação com regressão logística entre as variáveis e a ocorrência de óbito. Resultados: foram estudados 288 pacientes, com 430 lesões; 92,7% era do sexo masculino, 49,7% entre 25 e 49 anos de idade; 47,2% das lesões foi ocasionada por projéteis de arma de fogo; 47,2% das lesões situava-se nos membros superiores, 42,7% nos membros inferiores, 8% em região cervical, 3,1% torácicas e 0,7% abdominais; 52,8% dos pacientes teve hospitalização por sete dias ou menos. Amputação foi necessária em 6,9% e a mortalidade foi 7,93%. Conclusão: distâncias superiores a 200km foram associadas à internação prolongada e maior probabilidade de amputação de membros. Foi encontrada correlação significativa entre a ocorrência de óbito e o fato de haver lesão arterial, lesão vascular na topografia cervical e lesão vascular na topografia torácica.

ABSTRACT Objective: to evaluate the epidemiological data of patients operated on due to vascular trauma at a referral hospital in Pará state, to determine the variables that increase the risk of death, and to make a comparative analysis with the results previously published by the same institution. Methods: an analytical retrospective study was performed through data collection from patients operated due to vascular injuries, between March 2013 and March 2017. Demographic and epidemiological data, such as the mechanism and topography of the lesion, distance between the trauma site and the hospital, and type of treatment and complications, were analyzed. Multivariate analysis and logistic regression studies were performed, to evaluate significant dependence between some variables and death occurrence. Results: two hundred and eighty eight patients with 430 lesions were studied; 92.7% were male, 49.7% were between 25 and 49 years old; 47.2% of all injuries were caused by firearm projectiles; 47.2% of the lesions were located in the upper limbs, 42.7% in the lower limbs, 8% in the cervical region, 3.1% in the thoracic region, and 0.7% in the abdominal region; 52.8% of the patients were hospitalized for seven days or less. Amputation was required in 6.9% of patients and there was mortality in 7.93% of the cases. Conclusion: distances greater than 200km were associated with prolonged hospitalization and greater probability of limb amputation. Significant correlation between death occurrence and arterial injury, vascular injury in the cervical region, and vascular injury in the thoracic region was found.

Disección espontánea de la arteria circunfleja: un caso poco frecuente / Spontaneous dissection of the circumflex artery: a rare case

La disección espontánea de las arterias del árbol coronario es una causa poco frecuente de síndrome coronario agudo. Afecta predominantemente a mujeres sin factores de riesgo cardiovasculares. Se presenta el caso de una paciente de 46 años de edad sin antecedentes de relevancia con precordialgia típica sin cambios en el electrocardiograma con elevación enzimática. A las 24hs repite episodio anginoso por lo que se realiza cinecoronariografía en donde se evidencia una disección espontánea helicoidal de la arteria circunfleja. Se lleva a cabo angioplastia con 3 stent metálicos. La paciente evolucionó asintomática durante el seguimiento...

Peripheral arterial embolism of pellets after shotgun injury to the abdomen: A case report.

Dealing with shotgun injury to the abdomen it is important to be aware of the possibility of missile emboli and their potential clinical effects because it usually causes vascular trauma but intravascular missile embolism is relatively rare. Vascular trauma following shotgun injuries may involve laceration of the vessel wall, pseudoaneurysm, arteriovenous fistula or missile embolism. A pellet embolus should be suspected in all cases where gunshot entry wound is present with or without an exit wound. We recently encountered a case of a close-range shotgun injury to the abdomen with subsequent embolisation of pellets to bifurcation of popliteal artery both lower limbs. However, pellet embolus is asymptomatic, there is still debate over best management because conservative management avoids surgical risks and operative removal prevents the possibility of embolus related life threatening complications. This case shows that it is necessary to do whole body imaging in all cases of shotgun injury whether exit wound present or not.

Priapismo de bajo flujo convertido en priapismo de alto flujo por fístula arterio-lacunar secundaria a la técnica de Winter / Low-flow priapism developing to high-flow priapism by arterial-lacunar fistula secondary to the winter procedure

El priapismo es una afección patológica que consiste en una erección peneana persistente más allá de la estimulación sexual. Presentamos el caso de un paciente de 80 años, diagnosticado inicialmente, por la historia clínica, valores gasométricos de los cuerpos cavernosos y ultrasonografía doppler color peneana, de priapismo de bajo flujo que durante la realización de la técnica de Winter se produce iatrogénicamente la laceración bilateral de las arterias dorsales, originando una fístula arteriolacunar y en consecuencia un priapismo de alto flujo. Se realizó arteriografía selectiva de la pudenda, al no ser la eco-doppler color concluyente, que puso de manifiesto dicha fístula y permitió la embolización supraselectiva con microcoils...

Priapism is a pathology consisting of prolonged penile erection unrelated to sexual stimulation. We present an 80-year-old patient with relevant clinical history; corpora cavernosa blood gas analysis and penile Doppler ultrasound examination confirmed low-flow priapism. The Winter procedure was performed, which provoked iatrogenic laceration of the dorsal artery, leading to an arterio-lacunar fistula and high-flow priapism. A second Doppler ultrasound was inconclusive, and so a selective angiography was performed to observe the pudendal artery, following which selective embolization with microcoils was carried out...

Traumas vasculares: estadísticas de un bienio en la provincia de Santiago de Cuba / Vascular trauma: statistics of a biennium in Santiago de Cuba province

Se realizó un estudio observacional, descriptivo y transversal de 71 pacientes que sufrieron trauma vascular en la ciudad de Santiago de Cuba durante el bienio 2008- 2010, con vistas a determinar la morbilidad y mortalidad por esa causa en el territorio, para lo cual se obtuvo información sobre variables sociodemográficas y clínicas. Entre los principales resultados sobresalió el predominio de su ocurrencia en los varones de 16-30 años, del arma blanca como agente desencadenante y de las lesiones en las extremidades superiores; pero aunque frecuentes, apenas se complican y son raramente mortales.

A descriptive, observational, and cross-sectional study of 71 patients undergoing vascular trauma was carried out in Santiago de Cuba during the biennium 2008-2010 in order to determine the morbidity and mortality due to that cause in the territory, in which case data about clinical and socio-demographical variables was obtained. The predominance of its occurrence in males aged 16-30 years, as well as the predominance of white weapon being the triggering factor and causing the injuries in upper extremities prevailed among the main results; in spite of being common, these cases do not complicate and are rarely fatal.

Pseudoaneurisma post traumático de la arteria pedia: caso clínico / Post traumatic pseudoaneurysm of the pedal artery: case report

Pseudoaneurysm of the pedal artery is an uncommon condition that is usually caused by a traumatic injury or an iatrogenic intervention. The patient usually complains of an enlarging painless, pulsatile mass. We report a previously healthy 49 years old male presenting with a pulsatile mass of his left foot and a history of a traumatic lesion in the zone three months ago. A Doppler ultrasound examination confirmed the presence of a pseudoaneurysm of the pedal artery of 2.6 x 1.5 cm diameter. The patient underwent surgical resection of the mass and suture ligation of the artery. The postoperative period was uneventful.

Los pseudoaneurismas de la arteria pedia son infrecuentes y habitualmente se generan secundariamente a un traumatismo o a una intervención iatrogénica. Presentamos el caso de un paciente sano de 49 años que presenta un aumento de volumen pulsátil 3 meses posterior al traumatismo contuso de su pie izquierdo. En el doppler color se evidencia la presencia de un pseudoaneurisma de la arteria pedia de 2,64 x 1,53 cm. El paciente fue intervenido con resección y ligadura de la arteria con buena evolución postoperatoria.

Trauma vascular: nuestra experiencia en los últimos 10 años / Trauma vascular- nossa experiência nos últimos 10 anos. / Vascular trauma: ouer experience in the last 10 years

Antecedentes: El incremento de la violencia ciudadana por el uso de armas de fuego y blancas en delitos comunes y los accidentes por exceso de velocidad sin medidas de seguridad adecuadas, han producido un aumento en la incidencia de los traumas vasculares, siendo la mayor causa de muerte en pacientes jóvenes. Objetivo: Demostrar nuestra casuística y experiencia en el manejo del trauma vascular así como su resolución. Diseño: Análisis descriptivo y retrospectivo de los últimos 10 años. Material y Método: 470 pacientes se tra taron desde el 1 de enero de 2000 hasta el 31 diciembre del 2009. Se analizó la composición demográfica, el mecanismo lesional, la región afectada y la técnica quirúrgica utilizada. El 86,6% fue de sexo masculino y el 13,4% de sexo femenino. La edad promedio fue de 26,9 años. El 69,5% presentaron trauma penetrante y el 30,5% trauma contuso. El 4,5% presentaron lesiones de cuello, 12% torácicas, 14,9% lesiones abdominales y nuestra mayor casuística fue la lesión de los miembros: 68,6%. En 175 pacientes, la técnica fue el bypass (119 venosos y 56 protésicos ). 206 pacientes recibieron resección y anastomosis término-terminal y 36 pacientes fueron tratados con ligadura primaria. Como métodos endovasculares se colocaron 5 endoprótesis por ruptura traumática de aorta torácica, 3 stents periféricos y se realizó un reimplante de mano. Resultados: La mortalidad global fue del 7,8% (37 pacientes) en la mayoría de los casos debido al politrauma, Crush síndrome, SIRS y/o shock séptico. En cuanto a los pacientes con RTAT, uno presentó óbito por falla del material. El 9,1% de los pacientes sufrieron amputación del miembro (38 pacientes) de los cuales 9 fueron por arrancamiento del miembro, 11 amputaciones primarias y 18 secundarias. Del total de pacientes que presentaron lesiones vasculares de los miembros, 60 (5,8%) recibieron fasciotomía pre, intra o post-revascularización. Conclusiones: Nuestra aceptable morbimortalidad depende de la rapidez y ...

Antecedentes: O aumento da violência nas cidades, o uso de armas de fogo e armas brancas em delitos comuns, e os acidentes por excesso de velocidade sem medidas de segurança adequadas, têm produzido um aumento na incidência dos traumas vasculares, sendo esta, a maior causa de morte em pacientes jovens. Objetivo: Demonstrar nossa especificidade e experiência no tratamento do trauma vascular, como também em sua resolução. Desenho: Análise descritiva e retrospectiva dos últimos 10 anos. Material e Método: 470 pacientes foram tratados de 1º de janeiro de 2000 a 31 de dezembro de 2009. Analisou-se a composição demográfica, o mecanismo de lesão, a região afetada e a técnica cirúrgica utilizada. 86, 6 % dos pacientes eram do sexo masculino e 13,4 % do sexo feminino. A idade média foi de 26,9 anos. 69,5 % apresentaram trauma penetrante e 30,5 % trauma contuso. 4,5 % apresentaram lesões no pescoço, 12 % torácicas, 14,9 % lesões abdominais e a nossa maior especificidade, em 68,6% dos casos, foi a lesão de membros. Em 175 pacientes a técnica foi o bypass (119 venosos e 56 com próteses ). 206 pacientes receberam ressecção e anastomose término-terminal e 36 pacientes foram tratados com ligadura de tipo primário. Como métodos endovasculares, foram colocadas 5 endopróteses por ruptura traumática de Aorta torácica, 3 stents periféricos, e realizou-se um reimplante de mão. Resultados: A mortalidade global foi de 7,8 % (37 pacientes), na maioria dos casos devido ao politrauma, síndrome de Cushing, SIRS (síndrome da resposta inflamatória sistêmica), e/ou choque séptico. Quanto aos pacientes com RTAT, um deles apresentou óbito por falha do material. 9,1 % dos pacientes sofreram amputação de membro (38 pacientes), dos quais 9 foram por arrancamento de membro, 11 amputações primárias e 18 secundárias. Do total de pacientes que apresentaram lesões vasculares de membros, 60 (5,8 %) receberam fasciotomia pré, intra ou pós revascularização. Conclusões: Nossa aceitável ...

Background: The increase of the urban violence due to the use of fire and white weapons in common crimes as well as the accidents because of the excess of speed without the corresponding safe security measures have produced an increase in the incidence of the vascular traumas, being the most important cause of death in young patients. Objective: To show casuisty and experience in the management of the vascular trauama as well as its resolution. Design: Descriptive and retrospective analyses during the last 10 years. Material and Method: 470 patients were treated from January 1, 2000 up to December 2009. The demographic composition, the lesional mechanism, the affected area and the surgical technique were analysed. The 86.6% were male and the 13.4% female. The average age was 26.9%. The 69.5% have presented penetrant trauma and the 30.5% blunt trauma. The 4.5% have presented injuries on the neck, 12% thoracic ones, 14.9% abdominal ones and our greatest casuistic was the injueries on the arms. In 175 patients the technique was the bypass (119 venous and 56 prothetic ones). 206 patients have received resection and termino-terminal anastomosis and 36 patients were treated with primary binding. As endovascular methods, 5 stents for traumatic rupture of thoracic aorta, 3 peripheral stents and a hand reimplantation were used. Results: The global mortality was of the 7.8% 37 patients), in most of the cases due to the poly-trauma, Crush syndrome, SIRS, and/or septic shock. Regarding to the patients with RTAT, on of them, death has been presented due to material failure. The 9.1% of the patients have suffered from amputation of the member (38 patients), from whom 9 of them were for pulling member, 11 for primary amputations and 18 secondary ones. From the total of the patients that have presented vascular injuries of the members, 60 (5.8%) have received fasciotomy pre, intra or post revascularization. Conclusions: Our acceptable mortality depends on the quickness and ...

Trauma vascular de extremidad superior: manejo en la etapa aguda / Vascular trauma of an upper extremity: management in the acute stage

El trauma vascular es una situación de emergencia a la cual podemos vernos enfrentados en la unidad de urgencia, la cual puede causar la muerte del paciente de no realizar un manejo oportuno. Las extremidades representan el principal sitio de lesión en la población civil y de éstas alrededor del 30 por ciento afectan la extremidad superior. La principal etiología es el trauma penetrante, específicamente por arma de fuego, existiendo además un aumento alarmante de las lesiones iatrogénicas. El cirujano de urgencia debe tener los conocimientos teóricos y prácticos que le permitan un adecuado diagnóstico, y manejo en la etapa aguda, siendo el objetivo fundamental la sobrevida del paciente y luego el salvataje de la extremidad. La indicación actual ante la presencia de signos duros es la exploración quirúrgica clásica, existiendo algunos pacientes que podrían ser resueltos por cirugía endovascular, específicamente pacientes estables hemodinámicamente con lesiones de la arteria axilar y braquial proximal. En el presente artículo se exponen las consideraciones básicas en el manejo de emergencia del paciente con trauma vascular de extremidad superior.

The vascular trauma is an emergency situation at which we may be confronted in the emergency unit. This may cause the patient’s death if not made a timely management. The limbs represent the main site of injury in civilian population. 30 percent affect the upper extremity. The main etiology is penetrating trauma, specifically gunshot. There is also an alarming increase of iatrogenic injuries. The emergency surgeon should have an appropriate theoretical and practical knowledge to allow a proper diagnosis, and management in the acute stage. The main objective is to keep the patient alive and then the rescue of the limb. The current indication in the presence of objective signs is the classic surgical exploration, and there are some patients who could be resolved by endovascular surgery, specifically hemodynamically stable patients with injuries of the proximal brachial and axillary artery. This article presents the basic considerations in the emergency management of patients with upper extremity vascular trauma.

Factores que complican las lesiones vasculares periféricas abordadas quirúrgicamente en el período de enero a junio 2009: Hospital Escuela Doctor Roberto Calderón Gutiérrez / Factors complicating peripheral vascular lesions surgically addressed in the period from January to June 2009: Doctor Roberto Calderon Hospital Escuela Gutierrez

Se realizó un estudio descriptivo, de corte transversal, retrospectivo en el que se incluyeron 52 pacientes con diagnostico de lesión vascular periférica, las cuales fueron abordadas quirúrgicamente en el Hospital Escuela “Dr. Roberto Calderón G.” en el período de Enero 2005 a Junio 2009.El grupo etario más afectado fue de 15 a 29 años, predominando el sexo masculino en un 98%. La causa principal de las lesiones vasculares periféricas fue la violencia, las ocasionadas por arma de fuego fueron las más frecuentes afectando a miembros inferiores en un 55.8%, donde los vasos femorales, arteria y vena, fueron lesionados en un 18.6% y 20% respectivamente, en tanto, las lesiones ocasionadas por arma blanca afectaron a miembros superiores, lesionando a los vasos humerales.El tiempo transcurrido entre la lesión y el tratamiento quirúrgico correctivo tuvo una media de 334.22 minutos. La duración de la intervención quirúrgica tuvo una media de 165.63 minutos. En promedio los pacientes estuvieron ingresados en el centro hospitalario 8.27 días. El diagnóstico se realizó de forma clínica. El vaso más frecuentemente lesionado fue la arteria. La lesión circunferencial que predominó fue el 100% del vaso, lo cual tiene relación con el daño vascular en el que predominó la transección.El manejo más frecuente en las lesiones venosas fue la ligadura y en las lesiones arteriales fue la anastomosis termino-terminal. En un caso se realizó amputación. En 17 casos fasciotomía predominando las indicadas terapéuticamente. Las complicaciones presentadas fueron: la infección del sitio quirúrgico y el Síndrome Compartimental. Se aplicó el antibiótico profiláctico en 57.7% y se usó anticoagulante intraoperatorio en el 48.1%. El 80.77% continuaron con su esquema de antibioticoterapia en su postquirúrgico. Hubo un reingreso por infección del sitio quirúrgico. No se reportaron fallecidos...

Asociación patomorfológica y morfométrica de la lesión aterosclerótica en siete diferentes sectores arteriales / Pathomorphological and morphometric association of the atherosclerotic lesion in seven different arterial sectors

Se investigaron 460 necropsias de pacientes procedentes del Hospital Docente Dr Carlos J Finlay, realizadas entre 1999 y 2003. Se analizaron 18 arterias procedentes de los siete sectores vasculares siguientes: el polígono de Willis, considerado como una sola arteria, las tres coronarias epicárdicas (derecha, descendente anterior y circunfleja izquierda), la aorta (torácica y abdominal), las renales, las ilíacas y las femorales. Para el estudio patomorfológico y morfométrico se utilizó el sistema aterométrico. Las arterias se disecaron, se fijaron, se colorearon y se les realizaron los análisis cualitativo y cuantitativo para el estudio estadístico mediante la correlación canónica. Entre los resultados más relevantes se observaron muy fuertes correlaciones entre la estría adiposa, la placa fibrosa y la placa grave en los análisis entre todas las arterias investigadas, con algunas excepciones. El conjunto de estos resultados sugiere que la aterosclerosis es un proceso de distribución sistémica.

Four hundred and sixty necropsies of patients from Carlos J Finlay Hospital performed between 1999 and 2003 were investigated. Eighteen arteries from the following seven vascular arteries were analyzed: Willis circle, considered as only one artery, the three epicardial coronaries (right, anterior descending and left circumflex), the aorta (thoracic and abdominal); the two renal, the iliac and the phemoral. An atherometric system was used for the pathomorphological and morphometric study. The arteries were dissected, fixed and coloured. A qualitative and quantitative analysis was made for the statistical study by canonical correlation. Among the most important results there were observed very strong correlations between the adipose stria, the fibrous plaque and the severe plaque in the analyses of all among all the investigated arteries, with a few exceptions. All these results strongly suggest that atherosclerosis is a process of systemic distribution.

Alterações vasculares da hipertensão arterial / Vascular modifications of arterial hypertension

As principais complicações da hipertensão arterial são consequências de lesões vasculares. As alterações da estrutura e função das pequenas artérias de resistência em reposta ao aumento de tensão na parede da artéria incluem espessamento arterial, diminuição do lúmen e vasoconstrição aumentada. As grandes artérias que apresentam capacidade de condução e de amortecimento respondem ao aumento de pressão com aumento da rigidez e diminuição da distensibilidade, que piora com o envelhecimento. O aumento da rigidez no paciente hipertenso está associado a maior risco cardiovascular, assim como o remodelamento inadequado das pequenas artérias. As principais manifestações clínicas das lesões vasculares da hipertensão arterial incluem a hipertensão maligna, a doença arterial periférica, o auneurisma e a dissecção da aorta. O tratamento adequado da pressão arterial pode reverter as lesões vasculares e consequentemente melhorar o prognóstico cardiovascular do paciente hipertenso.

Tratamento endovascular do trauma arterial dos membros / Endovascular management of extremity arterial trauma

Geralmente o tratamento das lesões arteriais traumáticas é realizado com técnicas tradicionais de revascularização. Cada vez mais, porém, as lesões vasculares podem ser corrigidas com eficiência por meio de procedimentos minimamente invasivos. Nós descrevemos quatro casos de trauma arterial dos membros que foram tratados por técnicas endovasculares num centro de referência. Todos os pacientes evoluíram satisfatoriamente durante o seguimento de 15 meses. Nós sugerimos que o tratamento endovascular é uma alternativa promissora em relação à cirurgia para pacientes selecionados com trauma arterial dos membros.

Treatment of arterial traumatic injuries is usually performed with conventional revascularization techniques. However, vascular injuries can increasingly be repaired efficiently through minimally invasive procedures. We report four cases of extremity arterial trauma treated by endovascular techniques in a reference center. All patients showed satisfactory development over a 15-month follow-up. We suggest that endovascular therapy is a promising alternative to surgery for selected patients with extremity arterial trauma.

Anti-inflammatory Effect of Abciximab-Coated Stent in a Porcine Coronary Restenosis Model

The aim of this study was to examine the anti-inflammatory effect of abciximab-coated stent in a porcine coronary overstretch restenosis model. Ten abciximab-coated stents, ten sirolimus-eluting stents (SES), and ten paclitaxel-eluting stents (PES) were deployed with oversizing (stent/artery ratio 1.3:1) in porcine coronary arteries, and histopathologic analysis was done at 28 days after stenting. There were no significant differences in the neointima area normalized to injury score and inflammation score among the three stent groups (1.58+/-0.43 mm2, 1.57+/-0.39 mm2 in abciximab-coated stent group vs. 1.69+/-0.57 mm2, 1.72+/-0.49 mm2 in the SES group vs. 1.92+/-0.86 mm2, 1.79+/-0.87 mm2 in the PES group, respectively). In the neointima, most inflammatory cells were lymphohistiocytes. Significant positive correlations were found between the extent of inflammatory reaction and the neointima area (r=0.567, p<0.001) and percent area stenosis (r=0.587, p<0.001). Significant correlations were found between the injury score and neointimal area (r=0.645, p<0.001), between the injury score and the inflammation score (r=0.837, p<0.001), and between the inflammation score and neointimal area (r=0.536, p=0.001). There was no significant difference in the inflammatory cell counts normalized to injury score among the three stent groups (75.5+/-23.1/microliter in abciximabcoated stent group vs. 78.8+/-33.2/microliter in the SES group vs. 130.3+/-46.9/microliter in the PES group). Abciximab-coated stent showed comparable inhibition of inflammatory cell infiltration and neointimal hyperplasia with other drug-eluting stents in a porcine coronary restenosis model.

Clinical Features of Pseudoaneurysms Complicating Pancreatitis: Single Center Experience and Review of Korean Literature / 대한소화기학회지

BACKGROUND/AIMS: Pseudoaneurysm is a life-threatening complication of chronic or acute pancreatitis. This study was undertaken to evaluate the clinical features of pseudoaneurysm complicating pancreatitis. METHODS: We reviewed the medical records of 7 patients diagnosed as pseudoaneurysms with chronic pancreatitis in Korea University Guro and Anam Hospital from January 1995 to March 2006 and analyzed their demographics, clinical courses and outcomes. RESULTS: All patients were men and mean age was 54.6 years (range, 43-67 years). All the cases occurred in the setting of chronic alcoholic pancreatitis complicated by pseudocyst. Abdominal pain was the unique initial clinical symptom in 5 cases, hematemesis in 1 case, and simultaneous abdominal pain with hematemesis in 1 case. Bleeding into pseudocyst developed in 5 cases, flowing into duodenum through pancreatic duct in 1 case and rupture into the descending colon in 1 case. Mean duration between onset of symptom and diagnosis of pseudoaneurysm was 7.8 days (range, 1-23 days). Six cases were diagnosed by abdominal computed tomography disclosing characteristic finding of focal high density area in the pseudocyst. Pulsed doppler abdominal sonography was performed before computed tomography in 3 cases and results were negative in 2 cases. Transcatheter arterial embolizations were initially performed in 6 cases, and there was no recurrent bleeding except one case of splenic infarction. Distal pancreatectomy was initially performed in 1 case. CONCLUSIONS: Pseudoaneurysms complicating chronic pancreatitis shows various clinical features. Transcatheter arterial embolization can be recommended as a primary therapeutic modality.

Upper limb arterial injury: Management and Outcome

In this study we are aiming to document and analyse the roles of arterial damage and associated injuries on long-term functional outcomes after upper extremity arterial trauma. In this retrospective study we reviewed patients who presented with an arterial injury to the upper limb during the period between [2003 to 2006]. The location and management of the arterial injuries, the nature and severity of concomitant nerve injuries and the overall degree of disability in the survivors were determined. 68 patients were included in this study. 34 patients [50%] sustained blunt injuries, 33 [48.5%] were presented with penetrating injuries, and one patient sustained firearm injury. The most common site of arterial injury was the brachial artery 36 patients [52.9%]. The most common method of surgical management was an autogenous vein interposition graft, placed in 24 patients [35.3%]. 28 patients were suffered serious upper limb fractures such as supracondylar fracture humerous. There were 19 nerve injuries. Residual disability was present in 13 patients [19%]. Only 2 patients had complete recovery of the injured nerves. Associated injuries, rather than the vascular injury, are the cause of long-term disability in the multisystem trauma victim who has upper extremity arterial injury

Laceration of the posterior inferior cerebellar artery by suboccipital puncture of the cisterna magna: case report

Relatamos o caso de um homem de 27 anos que procurou o pronto atendimento de um hospital com cefaléia intensa, vômitos e um episódio de perda de consciência. Uma tomografia de crânio foi normal e o paciente foi dispensado. Dez horas após, o paciente procurou o setor de emergência do nosso hospital com as mesmas queixas. Uma punção suboccipital tecnicamente dificultada pela ansiedade do paciente que se movimentou durante a coleta foi realizada evidenciando amostra de LCR levemente hemorrágico. A análise do LCR mostrou presença de 1600 hemácias íntegras sem aumento de leucócitos nem alterações bioquímicas. Houve piora acentuada da cefaléia e após 6 horas apresentou sonolência, torpor e sinais de descerebração. Nova tomografia mostrou sangue no espaço subaracnóideo e nos ventrículos. Uma angiografia realizada de emergência demonstrou laceração da artéria cerebelar póstero-inferior esquerda com a formação de um pseudoaneurisma. O paciente foi de imediato operado tendo sido realizada a clipagem do pseudoaneurisma com sucesso. Dezesseis dias após o paciente teve alta com exame neurológico normal.